QIMR Berghofer
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Editorial: Mouse Models of Hematopoietic Stem Cell Transplantation.
Varelias, Antiopi; Zhang, Ping; Hashimoto, Daigo
Frontiers in Immunology - 1/01/2022
A Phase 3 Double-Blind Study of the Addition of Tocilizumab versus Placebo to Cyclosporin/Methotrexate GvHD Prophylaxis.
Kennedy, Glen; Tey, Siok-Keen; Buizen, Luke; Varelias, Antiopi; Gartlan, Kate H; Curley, Cameron; Olver, Stuart; Chang, Karshing; Butler, Jason; Misra, Ashish; Subramoniapillai, Elango; Morton, Anthony; Durrant, Simon; Henden, Andrea S; Moore, John; Ritchie, David S; Gottlieb, David; Cooney, Julian P; Paul, Sanjoy K; Hill, Geoffrey R
BLOOD - 1/01/2021
CMV exposure drives long-term CD57+ CD4 memory T cell inflation following allogeneic stem cell transplant.
Yeh, Albert C; Varelias, Antiopi; Reddy, Anupama; Barone, Sierra M; Olver, Stuart; Chilson, Kate; Onstad, Lynn; Ensbey, Kathleen S; Henden, Andrea S; Samson, Luke; Jaeger, Carla A; Bi, Timothy; Dahlman, Kimberly; Kim, Tae Kon; Zhang, Ping; Degli-Esposti, Mariapia A; Newell, Evan W; Jagasia, Madan; Irish, Jonathan Michael; Lee, Stephanie J; Hill, Geoffrey R
BLOOD - 1/01/2021
IFN? Therapy Prevents Severe Gastrointestinal Graft-versus-Host Disease.
Henden, Andrea S; Koyama, Motoko; Robb, Renee J; Forero, Adriana; Kuns, Rachel D; Chang, Karshing; Ensbey, Kathleen S; Varelias, Antiopi; Kazakoff, Stephen H; Waddell, Nicola; Clouston, Andrew D; Giri, Rabina; Begun, Jakob; Blazar, Bruce R; Degli-Esposti, Mariapia A; Kotenko, Sergei V; Lane, Steven W; Bowerman, Kate; Savan, Ram; Hugenholtz, Philip; Gartlan, Kate H; Hill, Geoffrey R
BLOOD - 1/01/2021
Adults with Plasmodium falciparum malaria have higher magnitude and quality of circulating T-follicular helper cells compared to children.
Oyong, Damian A; Loughland, Jessica R; Soon, Megan S F; Chan, Jo-Anne; Andrew, Dean; Wines, Bruce D; Hogarth, P Mark; Olver, Stuart D; Collinge, Alika D; Varelias, Antiopi; Beeson, James G; Kenangalem, Enny; Price, Ric N; Anstey, Nicholas M; Minigo, Gabriela; Boyle, Michelle J
EBioMedicine - 1/01/2021
Continuous pre- and post-transplant exposure to a disease-associated gut microbiome promotes hyper-acute graft-versus-host disease in wild-type mice.
Bowerman, Kate L; Varelias, Antiopi; Lachner, Nancy; Kuns, Rachel D; Hill, Geoffrey R; Hugenholtz, Philip
Gut Microbes - 1/07/2020
Cancer Council Queensland project grant - 1129969
Single-cell transcriptomics of allo-reactive CD4+ T cells over time reveals divergent fates during gut GVHD.
Engel, Jessica A; Lee, Hyun Jae; Williams, Cameron G; Kuns, Rachel D; Olver, Stuart; Lansink, Lianne Im; Soon, Megan Sf; Andersen, Stacey B; Powell, Joseph E; Svensson, Valentine; Teichmann, Sarah A; Hill, Geoffrey R; Varelias, Antiopi; Koyama, Motoko; Haque, Ashraful
JCI INSIGHT - 1/07/2020
Single-cell transcriptomics of allo-reactive CD4+ T cells over time reveals divergent fates during gut GVHD.
Engel, Jessica A; Lee, Hyun Jae; Williams, Cameron G; Kuns, Rachel D; Olver, Stuart; Lansink, Lianne Im; Soon, Megan Sf; Andersen, Stacey B; Powell, Joseph E; Svensson, Valentine; Teichmann, Sarah A; Hill, Geoffrey R; Varelias, Antiopi; Koyama, Motoko; Haque, Ashraful
JCI INSIGHT - 1/06/2020
ASC modulates CTL cytotoxicity and transplant outcome independent of the inflammasome.
Cheong, Melody; Gartlan, Kate H; Lee, Jason S; Tey, Siok-Keen; Zhang, Ping; Kuns, Rachel D; Andoniou, Christopher E; Martins, Jose Paulo; Chang, Karshing; Sutton, Vivien R; Kelly, Greg; Varelias, Antiopi; Vuckovic, Slavica; Markey, Kate A; Boyle, Glen M; Smyth, Mark J; Engwerda, Christian R; MacDonald, Kelli P A; Trapani, Joseph A; Degli-Esposti, Mariapia A; Koyama, Motoko; Hill, Geoffrey R
Cancer Immunology Research - 1/05/2020
Diverse IL-6 signalling modalities drive pathogenic T cell differentiation and graft-versus-host-disease after allotransplantation
Gartlan, Kate H.; Wilkinson, Andrew; Chang, Karshing; Kuns, Rachel D.; Henden, Andrea; Minnie, Simone A.; Ensbey, Kathleen S.; Clouston, Andrew; Zhang, Ping; Koyama, Motoko; Hidalgo, Juan; Rose-John, Stefan; Varelias, Antiopi; Vuckovic, Slavica; Hill, Geoffrey R.
JOURNAL OF IMMUNOLOGY - 1/05/2020
Continuous pre- and post-transplant exposure to a disease-associated gut microbiome promotes hyper-acute graft-versus-host disease in wild-type mice.
Bowerman, Kate L; Varelias, Antiopi; Lachner, Nancy; Kuns, Rachel D; Hill, Geoffrey R; Hugenholtz, Philip
Gut Microbes - 1/01/2020
Cancer Council Queensland project grant - 1129969
MAIT cells promote tumor initiation, growth and metastases via tumor MR1.
Yan, Juming; Allen, Stacey; McDonald, Elizabeth; Das, Indrajit; Mak, Jeffrey Y W; Liu, Ligong; Fairlie, David P; Meehan, Bronwyn S; Chen, Zhenjun; Corbett, Alexandra J; Varelias, Antiopi; Smyth, Mark J; Teng, Michele W L
CANCER DISCOVERY - 1/12/2019
NH&MRC Research Fellowship - 1078671
Pilot study investigating the effect of enteral and parenteral nutrition on the gastrointestinal microbiome post-allogeneic transplantation.
Andersen, Sarah; Staudacher, Heidi; Weber, Nicholas; Kennedy, Glen; Varelias, Antiopi; Banks, Merrilyn; Bauer, Judy
BRITISH JOURNAL OF HAEMATOLOGY - 1/10/2019
Pegylated interferon-2a invokes graft-versus-leukemia effects in patients relapsing after allogeneic stem cell transplantation.
Henden, Andrea S; Varelias, Antiopi; Leach, Justine; Sturgeon, Elise; Avery, Judy; Kelly, Jessica; Olver, Stuart; Samson, Luke; Hartel, Gunter; Durrant, Simon; Butler, Jason; Morton, Anthony J; Misra, Ashish; Tey, Siok-Keen; Subramoniapillai, Elango; Curley, Cameron; Kennedy, Glen; Hill, Geoffrey R
BLOOD ADVANCES - 1/10/2019
IL-6 dysregulation originates in dendritic cells and initiates graft-versus-host disease via classical signaling.
Wilkinson, Andrew N; Chang, Karshing; Kuns, Rachel D; Henden, Andrea S; Minnie, Simone A; Ensbey, Kathleen S; Clouston, Andrew D; Zhang, Ping; Koyama, Motoko; Hidalgo, Juan; Rose-John, Stefan; Varelias, Antiopi; Vuckovic, Slavica; Gartlan, Kate H; Hill, Geoffrey R
BLOOD - 1/10/2019
MHC Class II Antigen Presentation by the Intestinal Epithelium Initiates Graft-versus-Host Disease and Is Influenced by the Microbiota.
Koyama, Motoko; Mukhopadhyay, Pamela; Schuster, Iona S; Henden, Andrea S; Hülsdünker, Jan; Varelias, Antiopi; Vetizou, Marie; Kuns, Rachel D; Robb, Renee J; Zhang, Ping; Blazar, Bruce B; Thomas, Ranjeny; Begun, Jakob; Waddell, Nicola; Trinchieri, Giorgio; Zeiser, Robert; Clouston, Andrew D; Degli-Esposti, Mariapia A; Hill, Geoffrey R
IMMUNITY - 1/09/2019
NHLBI NIH HHS - R01 HL148164
PAG1 limits allergen-induced type 2 inflammation in the murine lung.
Ullah, Md Ashik; Vicente, Cristina T; Collinson, Natasha; Curren, Bodie; Sikder, Md Al Amin; Sebina, Ismail; Simpson, Jennifer; Varelias, Antiopi; Lindquist, Jonathan A; Ferreira, Manuel A R; Phipps, Simon
ALLERGY - 1/07/2019
Immune responses to the microbiome tune MHC class II antigen presentation by the intestinal epithelium to control gut pathology
Koyama, Motoko; Mukhopadhyay, Pamela; Schuster, Iona S.; Henden, Andrea S.; Hulsdunker, Jan; Varelias, Antiopi; Vetizou, Marie; Kuns, Rachel D.; Robb, Renee J.; Zhang, Ping; Blazar, Bruce R.; Thomas, Ranjeny; Begun, Jakob; Waddell, Nicola; Trinchieri, Giorgio; Zeiser, Robert; Clouston, Andrew D.; Degli-Esposti, Mariapia A.; Hill, Geoffrey R.
JOURNAL OF IMMUNOLOGY - 1/05/2019
Expansion of IL-17A-secreting CD8 + mucosa-associated invariant T cells in peripheral blood following stem cell mobilization.
Varelias, Antiopi; Gartlan, Kate H; Wilkinson, Andrew N; Olver, Stuart D; Samson, Luke D; Tey, Siok-Keen; MacDonald, Kelli P A; Hill, Geoffrey R
BLOOD ADVANCES - 1/03/2019
Phase I Trial of Inducible Caspase 9 T Cells in Adult Stem Cell Transplant Demonstrates Massive Clonotypic Proliferative Potential and Long-term Persistence of Transgenic T Cells.
Zhang, Ping; Raju, Jyothy; Ullah, Md Ashik; Au, Raymond; Varelias, Antiopi; Gartlan, Kate H; Olver, Stuart D; Samson, Luke D; Sturgeon, Elise; Zomerdijk, Nienke; Avery, Judy; Gargett, Tessa; Brown, Michael P; Coin, Lachlan J; Ganesamoorthy, Devika; Hutchins, Cheryl; Pratt, Gary R; Kennedy, Glen A; Morton, A James; Curley, Cameron I; Hill, Geoffrey R; Tey, Siok-Keen
CLINICAL CANCER RESEARCH - 1/02/2019
National Health and Medical Research Council (NHMRC, Australia) - APP1053135