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Targeting Vascular Endothelial-Cadherin in Tumor-Associated Blood Vessels Promotes T-cell-Mediated Immunotherapy
Zhao, Yang; Ting, Ka Ka; Li, Jia; Cogger, Victoria C.; Chen, Jinbiao; Johansson-Percival, Anna; Ngiow, Shin Foong; Holst, Jeff; Grau, Georges; Goel, Shom; Muller, Thorleif; Dejana, Elisabetta; McCaughan, Geoff; Smyth, Mark J.; Ganss, Ruth; Vadas, Mathew A.; Gamble, Jennifer R.
CANCER RESEARCH - 1/08/2017
National Health & Medical Research Council of Australia - 571408
G9a drives hypoxia-mediated gene repression for breast cancer cell survival and tumorigenesis
Casciello, Francesco; Al-Ejeh, Fares; Kelly, Greg; Brennan, Donal J.; Ngiow, Shin Foong; Young, Arabella; Stoll, Thomas; Windloch, Karolina; Hill, Michelle M.; Smyth, Mark J.; Gannon, Frank; Lee, Jason S.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA - 1/07/2017
National Health and Medical Research Council (NHMRC) - 107861
Interleukin (IL)-12 and IL-23 and Their Conflicting Roles in Cancer.
Yan, Juming; Smyth, Mark J; Teng, Michele W L
Cold Spring Harbor perspectives in biology - 1/07/2017
NK cell heparanase controls tumor invasion and immune surveillance
Putz, Eva M.; Mayfosh, Alyce J.; Kos, Kevin; Barkauskas, Deborah S.; Nakamura, Kyohei; Town, Liam; Goodall, Katharine J.; Yee, Dean Y.; Poon, Ivan K. H.; Baschuk, Nikola; Souza-Fonseca-Guimaraes, Fernando; Hulett, Mark D.; Smyth, Mark J.
JOURNAL OF CLINICAL INVESTIGATION - 1/06/2017
Erwin Schroedinger Fellowship of the Austrian Science Fund - J-3635
HDAC Inhibitor Panobinostat Engages Host Innate Immune Defenses to Promote the Tumoricidal Effects of Trastuzumab in HER2(+) Tumors
Medon, Mikolaj; Vidacs, Eva; Vervoort, Stephin J.; Li, Jason; Jenkins, Misty R.; Ramsbottom, Kelly M.; Trapani, Joseph A.; Smyth, Mark J.; Darcy, Phillip K.; Atadja, Peter W.; Henderson, Michael A.; Johnstone, Ricky W.; Haynes, Nicole M.
CANCER RESEARCH - 1/05/2017
PD1 functions by inhibiting CD28-mediated co-stimulation
O'Donnell, Jake S.; Smyth, Mark J.; Teng, Michele W. L.
Clinical & translational immunology - 1/05/2017
Dual-specific Chimeric Antigen Receptor T Cells and an Indirect Vaccine Eradicate a Variety of Large Solid Tumors in an Immunocompetent, Self-antigen Setting
Slaney, Clare Y.; von Scheidt, Bianca; Davenport, Alexander J.; Beavis, Paul A.; Westwood, Jennifer A.; Mardiana, Sherly; Tscharke, David C.; Ellis, Sarah; Prince, H. Miles; Trapani, Joseph A.; Johnstone, Ricky W.; Smyth, Mark J.; Teng, Michele W.; Ali, Aesha; Yu, Zhiya; Rosenberg, Steven A.; Restifo, Nicholas P.; Neeson, Paul; Darcy, Phillip K.; Kershaw, Michael H.
CLINICAL CANCER RESEARCH - 1/05/2017
Cancer Council of Victoria, Australia - 1066554
Targeting cancer-related inflammation in the era of immunotherapy
Nakamura, Kyohei; Smyth, Mark J.
IMMUNOLOGY AND CELL BIOLOGY - 1/04/2017
BK Polyomavirus: Clinical Aspects, Immune Regulation, and Emerging Therapies
Ambalathingal, George R.; Francis, Ross S.; Smyth, Mark J.; Smith, Corey; Khanna, Rajiv
CLINICAL MICROBIOLOGY REVIEWS - 1/04/2017
TIGIT and CD96: new checkpoint receptor targets for cancer immunotherapy
Dougall, William C.; Kurtulus, Sema; Smyth, Mark J.; Anderson, Ana C.
IMMUNOLOGICAL REVIEWS - 1/03/2017
Office of Extramural Research, National Institutes of Health - P01AI073748
Th17 plasticity and transition toward a pathogenic cytokine signature are regulated by cyclosporine after allogeneic SCT
Gartlan, Kate H.; Varelias, Antiopi; Koyama, Motoko; Robb, Renee J.; Markey, Kate A.; Chang, Karshing; Wilkinson, Andrew N.; Smith, David; Ullah, Md Ashik; Kuns, Rachel D.; Raffelt, Neil C.; Olver, Stuart D.; Lineburg, Katie E.; Teal, Bianca E.; Cheong, Melody; Teng, Michele W. L.; Smyth, Mark J.; Tey, Siok-Keen; MacDonald, Kelli P. A.; Hill, Geoffrey R.
BLOOD ADVANCES - 1/02/2017
IFN-gamma is required for cytotoxic T cell-dependent cancer genome immunoediting
Takeda, Kazuyoshi; Nakayama, Masafumi; Hayakawa, Yoshihiro; Kojima, Yuko; Ikeda, Hiroaki; Imai, Naoko; Ogasawara, Kouetsu; Okumura, Ko; Thomas, David M.; Smyth, Mark J.
Nature Communications - 1/02/2017
GVHD prevents NK-cell-dependent leukemia and virus-specific innate immunity
Bunting, Mark D.; Varelias, Antiopi; Souza-Fonseca-Guimaraes, Fernando; Schuster, Iona S.; Lineburg, Katie E.; Kuns, Rachel D.; Fleming, Peter; Locke, Kelly R.; Huntington, Nicholas D.; Blazar, Bruce R.; Lane, Steven W.; Tey, Siok-Keen; MacDonald, Kelli P. A.; Smyth, Mark J.; Degli-Esposti, Mariapia A.; Hill, Geoffrey R.
BLOOD - 1/02/2017
Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice
Overman, Jeroen; Fontaine, Frank; Moustaqil, Mehdi; Mittal, Deepak; Sierecki, Emma; Sacilotto, Natalia; Zuegg, Johannes; Robertson, Avril A. B.; Holmes, Kelly; Salim, Angela A.; Mamidyala, Sreeman; Butler, Mark S.; Robinson, Ashley S.; Lesieur, Emmanuelle; Johnston, Wayne; Alexandrov, Kirill; Black, Brian L.; Hogan, Benjamin M.; De Val, Sarah; Capon, Robert J.; Carroll, Jason S.; Bailey, Timothy L.; Koopman, Peter; Jauch, Ralf; Smyth, Mark J.; Cooper, Matthew A.; Gambin, Yann; Francois, Mathias
Elife - 1/01/2017
Resistance to PD1/PDL1 checkpoint inhibition
O'Donnell, Jake S.; Long, Georgina V.; Scolyer, Richard A.; Teng, Michele W. L.; Smyth, Mark J.
CANCER TREATMENT REVIEWS - 1/01/2017
Selective activation of anti-CD73 mechanisms in control of primary tumors and metastases
Vijayan, Dipti; Barkauskas, Deborah S.; Stannard, Kimberley; Sult, Erin; Buonpane, Rebecca; Takeda, Kazuyoshi; Teng, Michele W. L.; Sachsenmeier, Kris; Hay, Carl; Smyth, Mark J.
ONCOIMMUNOLOGY - 1/01/2017
National Health and Medical Research Council of Australia (NHMRC) Senior Research Fellowship - 1078671
Targeting cytokine signaling checkpoint CIS activates NK cells to protect from tumor initiation and metastasis
Putz, Eva M.; Guillerey, Camille; Kos, Kevin; Stannard, Kimberley; Miles, Kim; Delconte, Rebecca B.; Takeda, Kazuyoshi; Nicholson, Sandra E.; Huntington, Nicholas D.; Smyth, Mark J.
ONCOIMMUNOLOGY - 1/01/2017
National Health and Medical Research Council (NHMRC) - 1049407
Improved Efficacy of Neoadjuvant Compared to Adjuvant Immunotherapy to Eradicate Metastatic Disease
Liu, Jing; Blake, Stephen; Yong, Michelle; Harjunpaa, Heidi; Ngiow, Shin Foong; Takeda, Kazuyoshi; Young, Arabella; Allen, Stacey; Smyth, Mark J.; Teng, Michele W. L.
CANCER DISCOVERY - 1/12/2016
Mouse models in oncoimmunology
Zitvogel, Laurence; Pitt, Jonathan M.; Daillere, Romain; Smyth, Mark J.; Kroemer, Guido
NATURE REVIEWS CANCER - 1/12/2016