QIMR Berghofer
Publication Search
By Year 
Association of Genetic Variation With Keratoconus.
McComish, Bennet J; Sahebjada, Srujana; Bykhovskaya, Yelena; Willoughby, Colin E; Richardson, Andrea J; Tenen, Abi; Charlesworth, Jac C; MacGregor, Stuart; Mitchell, Paul; Lucas, Sionne E M; Mills, Richard A; Mackey, David A; Li, Xiaohui; Wang, Jie Jin; Jensen, Richard A; Rotter, Jerome I; Taylor, Kent D; Hewitt, Alex W; Rabinowitz, Yaron S; Baird, Paul N; Craig, Jamie E; Burdon, Kathryn P
JAMA ophthalmology - 1/12/2019
Author Correction: Gastroesophageal reflux GWAS identifies risk loci that also associate with subsequent severe esophageal diseases.
An, Jiyuan; Gharahkhani, Puya; Law, Matthew H; Ong, Jue-Sheng; Han, Xikun; Olsen, Catherine M; Neale, Rachel E; Lai, John; Vaughan, Tom L; Gockel, Ines; Thieme, René; Böhmer, Anne C; Jankowski, Janusz; Fitzgerald, Rebecca C; Schumacher, Johannes; Palles, Claire; , ; , ; Whiteman, David C; MacGregor, Stuart
Nature Communications - 1/12/2019
The relative impact of monogenic and polygenic risk variants on age at glaucoma diagnosis
Siggs, Owen; Souzeau, Emmanuelle; Han, Xikun; Qassim, Ayub; Ruddle, Jonathan; Vincent, Andrea; Best, Stephen; Casson, Robert; Graham, Stuart; Hewitt, Alex; Mackey, David; MacGregor, Stuart; Craig, Jamie
CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY - 1/11/2019
Multitrait analysis of glaucoma, intraocular pressure and vertical cup to disc ratio identifies many new loci and enables a polygenic genetic risk score strongly predictive of disease susceptibility in the population, and disease progression and treatment
Craig, Jamie; Han, Xikun; Qassim, Ayub; Hassall, Mark; Casson, Robert; Graham, Stuart; Landers, John; Willoughby, Colin; Lotery, Andrew; Wiggs, Janey; Siggs, Owen; Galanopoulos, Anna; Mitchell, Paul; Mills, Richard; Agar, Ashish; Healey, Paul; Vincent, Andrea; Mackey, David; Souzeau, Emmanuelle; Hewitt, Alex; MacGregor, Stuart
CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY - 1/11/2019
Multi-trait genome-wide association study identifies new loci associated with optic disc parameters.
Bonnemaijer, Pieter W M; Leeuwen, Elisabeth M van; Iglesias, Adriana I; Gharahkhani, Puya; Vitart, Veronique; Khawaja, Anthony P; Simcoe, Mark; Höhn, René; Cree, Angela J; Igo, Rob P; , ; , ; , ; Gerhold-Ay, Aslihan; Nickels, Stefan; Wilson, James F; Hayward, Caroline; Boutin, Thibaud S; Polašek, Ozren; Aung, Tin; Khor, Chiea Chuen; Amin, Najaf; Lotery, Andrew J; Wiggs, Janey L; Cheng, Ching-Yu; Hysi, Pirro G; Hammond, Christopher J; Thiadens, Alberta A H J; MacGregor, Stuart; Klaver, Caroline C W; Duijn, Cornelia M van
Communications Biology - 1/11/2019
NEI NIH HHS - R01 EY023242
High-throughput CRISPR-based morphological profiling of IOP-associated genes in primary trabecular meshwork cells
Lu, Peter; Hung, Sandy; Greatbatch, Connor; Liang, Helena; Liu, Rick; Mackey, David; Cook, Anthony; MacGregor, Stuart; Craig, Jamie; Hewitt, Alex
CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY - 1/11/2019
Higher incidence of incisional glaucoma surgery in Mendelian vs non-Mendelian glaucoma
Kuruvilla, Shilpa; Siggs, Owen; Souzeau, Emmanuelle; Ruddle, Jonathan; Hewitt, Alex; Mackey, David; Macgregor, Stuart; Landers, John; Mills, Richard; Craig, Jamie
CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY - 1/11/2019
Clinical phenotypes of glaucoma patients stratified by an intraocular pressure polygenic risk score
Qassim, Ayub; Souzeau, Emmanuelle; Siggs, Owen; Hassall, Mark; Han, Xikun; Gharahkhani, Puya; Hewitt, Alex; MacGregor, Stuart; Craig, Jamie E.; Lotery, Andrew J.; Willoughby, Colin E.; Vallabh, Neeru A.
CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY - 1/11/2019
Genome-wide association analysis of 95?549 individuals identifies novel loci and genes influencing optic disc morphology.
Han, Xikun; Qassim, Ayub; An, Jiyuan; Marshall, Henry; Zhou, Tiger; Ong, Jue-Sheng; Hassall, Mark M; Hysi, Pirro G; Foster, Paul J; Khaw, Peng T; Mackey, David A; Gharahkhani, Puya; Khawaja, Anthony P; Hewitt, Alex W; Craig, Jamie E; MacGregor, Stuart
HUMAN MOLECULAR GENETICS - 1/09/2019
Genetic heterogeneity in self-reported depressive symptoms identified through genetic analyses of the PHQ-9.
Thorp, Jackson G; Marees, Andries T; Ong, Jue-Sheng; An, Jiyuan; MacGregor, Stuart; Derks, Eske M
PSYCHOLOGICAL MEDICINE - 1/09/2019
Gastroesophageal reflux GWAS identifies risk loci that also associate with subsequent severe esophageal diseases.
An, Jiyuan; Gharahkhani, Puya; Law, Matthew H; Ong, Jue-Sheng; Han, Xikun; Olsen, Catherine M; Neale, Rachel E; Lai, John; Vaughan, Tom L; Böhmer, Anne C; Jankowski, Janusz; Fitzgerald, Rebecca C; Schumacher, Johannes; Palles, Claire; , ; , ; Whiteman, David C; MacGregor, Stuart
Nature Communications - 1/09/2019
The correlation between Glaucoma polygenic risk score and IOP measured by Icare (R) HOME tonometry within and outside of office hours
Awadalla, Mona S.; Hassall, Mark; Qassim, Ayub; Thi Thi Nguyen; Han, Xikun; MacGregor, Stuart; Landers, John; Craig, Jamie E.; Mackey, David A.; Hewitt, Alex W.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE - 1/07/2019
Glaucoma polygenic risk score predicts treatment intensity and RNFL loss in glaucoma suspects
Qassim, Ayub; Hassall, Mark; Han, Xikun; Marshall, Henry Nicholas; Awadalla, Mona S.; Graham, Stuart L.; Healey, Paul R.; Agar, Ashish; Landers, John; Galanopoulos, Anna; Casson, Robert James; Hewitt, Alex W.; MacGregor, Stuart; Craig, Jamie E.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE - 1/07/2019
Germline variation in DNA repair genes and risk of Barrett's esophagus and esophageal adenocarcinoma
Buas, Matthew F.; Yan, Li; Peng, Xuan; Qi, Qianya; Chen, Jianhong; Thrift, Aaron; He, Qianchuan; Onstad, Lynn; Gharahkhani, Puya; MacGregor, Stuart; Vaughan, Thomas L.; Madeleine, Margaret M.
CANCER RESEARCH - 1/07/2019
Genome-wide meta-analysis of keratinocytic cancers identifies 26 novel risk loci
Liyanage, Upekha E.; Law, Matthew H.; Han, Xikun; An, Jiyuan; Ong, Jue-Sheng; Gharahkhani, Puya; Iles, Mark M.; Neale, Rachel E.; Olsen, Catherine; Macgregor, Stuart; Whiteman, David C.
CANCER RESEARCH - 1/07/2019
Genetic risk scores of the largest multi-trait GWAS meta-analysis on refractive errors
Klaver, Caroline C. W.; Tedja, Milly S.; Han, Xikun; Verhoeven, Virginie J. M.; Ericksson, Nick; Furlotte, Nick; Amin, Najaf; van Duijn, Cornelia; MacGregor, Stuart
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE - 1/07/2019
Determining Possible Shared Genetic Architecture Between Myopia and Primary Open-Angle Glaucoma.
Iglesias, Adriana I; Ong, Jue Sheng; Khawaja, Anthony P; Gharahkhani, Puya; Tedja, Milly S; Verhoeven, Virginie J M; Bonnemaijer, Pieter W M; Wolfs, Roger C W; Young, Terri L; Jansonius, Nomdo M; Craig, Jamie E; Stambolian, Dwight; van Duijn, Cornelia M; MacGregor, Stuart; Klaver, Caroline C W; ,
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE - 1/07/2019
European Research Council (ERC) under the European Union's Horizon 2020 research and innovation programme - 648268
Association between coffee consumption and overall risk of being diagnosed with or dying from cancer among >300 000 UK Biobank participants in a large-scale Mendelian randomization study.
Ong, Jue-Sheng; Law, Matthew H; An, Jiyuan; Han, Xikun; Gharahkhani, Puya; Whiteman, David C; Neale, Rachel E; MacGregor, Stuart
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY - 1/07/2019
Australian National Health and Medical Research Council (NHMRC) - 1123248
A glaucoma polygenic risk score strongly associated with disease prediction and treatment intensity.
Craig, Jamie E.; Qassim, Ayub; Han, Xikun; Hassall, Mark; Casson, Robert James; Graham, Stuart L.; Mackey, David A.; Willoughby, Colin; Burdon, Kathryn P.; Landers, John; Souzeau, Emmanuelle; Wiggs, Janey L.; Hewitt, Alex W.; MacGregor, Stuart
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE - 1/07/2019
Author Correction: GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal effect of schizophrenia liability.
Pasman, Joëlle A; Verweij, Karin J H; Gerring, Zachary; Stringer, Sven; Sanchez-Roige, Sandra; Treur, Jorien L; Abdellaoui, Abdel; Nivard, Michel G; Baselmans, Bart M L; Ong, Jue-Sheng; Ip, Hill F; van der Zee, Matthijs D; Bartels, Meike; Day, Felix R; Fontanillas, Pierre; Elson, Sarah L; , ; de Wit, Harriet; Davis, Lea K; MacKillop, James; , ; , ; Derringer, Jaime L; Branje, Susan J T; Hartman, Catharina A; Heath, Andrew C; van Lier, Pol A C; Madden, Pamela A F; Mägi, Reedik; Meeus, Wim; Montgomery, Grant W; Oldehinkel, A J; Pausova, Zdenka; Ramos-Quiroga, Josep A; Paus, Tomas; Ribases, Marta; Kaprio, Jaakko; Boks, Marco P M; Bell, Jordana T; Spector, Tim D; Gelernter, Joel; Boomsma, Dorret I; Martin, Nicholas G; MacGregor, Stuart; Perry, John R B; Palmer, Abraham A; Posthuma, Danielle; Munafò, Marcus R; Gillespie, Nathan A; Derks, Eske M; Vink, Jacqueline M
NATURE NEUROSCIENCE - 1/06/2019