Medical and surgical care of mesothelioma patients and their relatives carrying germline BAP1 mutations.
Carbone, Michele; Pass, Harvey I; Ak, Guntulu; Alexander, H Richard; Baas, Paul; Baumann, Francine; Blakely, Andrew M; Bueno, Raphael; Bzura, Aleksandra; Cardillo, Giuseppe; Churpek, Jane E; Dianzani, Irma; De Rienzo, Assunta; Emi, Mitsuru; Emri, Salih; Felley-Bosco, Emanuela; Fennell, Dean A; Flores, Raja M; Grosso, Federica; Hayward, Nicholas K; Hesdorffer, Mary; Hoang, Chuong D; Johansson, Peter A; Kindler, Hedy L; Kittaneh, Muaiad; Krausz, Thomas; Mansfield, Aaron; Metintas, Muzaffer; Minaai, Michael; Mutti, Luciano; Nielsen, Maartje; O'Byrne, Kenneth; Opitz, Isabelle; Pastorino, Sandra; Pentimalli, Francesca; de Perrot, Marc; Pritchard, Antonia; Ripley, Robert Taylor; Robinson, Bruce; Rusch, Valerie; Taioli, Emanuela; Takinishi, Yasutaka; Tanji, Mika; Tsao, Anne S; Tuncer, A Murat; Walpole, Sebastian; Wolf, Andrea; Yang, Haining; Yoshikawa, Yoshie; Zolodnick, Alicia; Schrump, David S; Hassan, Raffit
Journal Of Thoracic Oncology : Official Publication Of The International Association For The Study Of Lung Cancer - 1/01/2022
Comparative Genomics Provides Etiologic and Biological Insight into Melanoma Subtypes
Newell, Felicity; Johansson, Peter A.; Wilmott, James S.; Nones, Katia; Lakis, Vanessa; Pritchard, Antonia L.; Lo, Serigne N.; Rawson, Robert, V; Kazakoff, Stephen H.; Colebatch, Andrew J.; Koufariotis, Lambros T.; Ferguson, Peter M.; Wood, Scott; Leonard, Conrad; Law, Matthew H.; Brooks, Kelly M.; Broit, Natasa; Palmer, Jane M.; Couts, Kasey L.; Vergara, Ismael A.; Long, Georgina, V; Barbour, Andrew P.; Nieweg, Omgo E.; Shivalingam, Brindha; Robinson, William A.; Stretch, Jonathan R.; Spillane, Andrew J.; Saw, Robyn P. M.; Shannon, Kerwin F.; Thompson, John F.; Mann, Graham J.; Pearson, John, V; Scolyer, Richard A.; Waddell, Nicola; Hayward, Nicholas K.
CANCER DISCOVERY - 1/01/2022
Combined inhibition of G9a and EZH2 suppresses tumor growth via synergistic induction of IL24-mediated apoptosis.
Casciello, Francesco; Kelly, Gregory M; Ramarao-Milne, Priya; Kamal, Nabilah; Stewart, Teneale A; Mukhopadhyay, Pamela; Kazakoff, Stephen H; Miranda, Mariska; Kim, Dorim; Davis, Felicity M; Hayward, Nicholas K; Vertino, Paula M; Waddell, Nicola; Gannon, Frank; Lee, Jason S
CANCER RESEARCH - 1/01/2022
Anatomic position determines oncogenic specificity in melanoma.
Weiss, Joshua M; Hunter, Miranda V; Cruz, Nelly M; Baggiolini, Arianna; Tagore, Mohita; Ma, Yilun; Misale, Sandra; Marasco, Michelangelo; Simon-Vermot, Theresa; Campbell, Nathaniel R; Newell, Felicity; Wilmott, James S; Johansson, Peter A; Thompson, John F; Long, Georgina V; Pearson, John V; Mann, Graham J; Scolyer, Richard A; Waddell, Nicola; Montal, Emily D; Huang, Ting-Hsiang; Jonsson, Philip; Donoghue, Mark T A; Harris, Christopher C; Taylor, Barry S; Xu, Tianhao; Chaligné, Ronan; Shliaha, Pavel V; Hendrickson, Ronald; Jungbluth, Achim A; Lezcano, Cecilia; Koche, Richard; Studer, Lorenz; Ariyan, Charlotte E; Solit, David B; Wolchok, Jedd D; Merghoub, Taha; Rosen, Neal; Hayward, Nicholas K; White, Richard M
NATURE - 1/01/2022
Multiomic profiling of checkpoint inhibitor-treated melanoma: Identifying predictors of response and resistance, and markers of biological discordance.
Newell, Felicity; Pires da Silva, Ines; Johansson, Peter A; Menzies, Alexander M; Wilmott, James S; Addala, Venkateswar; Carlino, Matteo S; Rizos, Helen; Nones, Katia; Edwards, Jarem J; Lakis, Vanessa; Kazakoff, Stephen H; Mukhopadhyay, Pamela; Ferguson, Peter M; Leonard, Conrad; Koufariotis, Lambros T; Wood, Scott; Blank, Christian U; Thompson, John F; Spillane, Andrew J; Saw, Robyn P M; Shannon, Kerwin F; Pearson, John V; Mann, Graham J; Hayward, Nicholas K; Scolyer, Richard A; Waddell, Nicola; Long, Georgina V
CANCER CELL - 1/01/2021
Germline variants are associated with increased primary melanoma tumor thickness at diagnosis.
Mangantig, Ernest; MacGregor, Stuart; Iles, Mark M; Scolyer, Richard A; Cust, Anne E; Hayward, Nicholas K; Montgomery, Grant W; Duffy, David L; Thompson, John F; Henders, Anjali; Bowdler, Lisa; Rowe, Casey; Cadby, Gemma; Mann, Graham J; Whiteman, David C; Long, Georgina V; Ward, Sarah V; Khosrotehrani, Kiarash; Barrett, Jennifer H; Law, Matthew H
HUMAN MOLECULAR GENETICS - 1/01/2021
Evolution of late-stage metastatic melanoma is dominated by aneuploidy and whole genome doubling.
Vergara, Ismael A; Mintoff, Christopher P; Sandhu, Shahneen; McIntosh, Lachlan; Young, Richard J; Wong, Stephen Q; Colebatch, Andrew; Cameron, Daniel L; Kwon, Julia Lai; Wolfe, Rory; Peng, Angela; Ellul, Jason; Dou, Xuelin; Fedele, Clare; Boyle, Samantha; Arnau, Gisela Mir; Raleigh, Jeanette; Hatzimihalis, Athena; Szeto, Pacman; Mooi, Jennifer; Widmer, Daniel S; Cheng, Phil F; Amann, Valerie; Dummer, Reinhard; Hayward, Nicholas; Wilmott, James; Scolyer, Richard A; Cho, Raymond J; Bowtell, David; Thorne, Heather; Alsop, Kathryn; Cordner, Stephen; Woodford, Noel; Leditschke, Jodie; O'Brien, Patricia; Dawson, Sarah-Jane; McArthur, Grant A; Mann, Graham J; Levesque, Mitchell P; Papenfuss, Anthony T; Shackleton, Mark
Nature Communications - 1/01/2021
Evaluation of Crizotinib Treatment in a Patient With Unresectable GOPC-ROS1 Fusion Agminated Spitz Nevi.
Robertson, Susan J; Orme, Lisa; Teixeira, Rodrigo; Shamassi, Maryam; Newell, Felicity; Patch, Ann-Marie; Yeh, Iwei; Gard, Grace; Wilmott, James; Jackett, Louise; LeBoit, Philip; Fellowes, Andrew; MacArthur, Grant; Fox, Stephen; Hayward, Nicholas K; Bastian, Boris; Scolyer, Richard; Waddell, Nicola; Penington, Anthony; Shackleton, Mark
JAMA Dermatology - 1/01/2021
G9a inhibition enhances checkpoint inhibitor blockade response in melanoma.
Kelly, Greg; Al-Ejeh, Fares; McCuaig, Robert D; Casciello, Francesco; Kamal, Nabilah; Ferguson, Blake; Pritchard, Antonia L; Ali, Sayed; Silva, Ines; Wilmott, James S; Long, Georgina V; Scolyer, Richard A; Rao, Sudha; Hayward, Nicholas K; Gannon, Frank; Lee, Jason S
CLINICAL CANCER RESEARCH - 1/01/2021
Novel MAPK/AKT-impairing germline NRAS variant identified in a melanoma-prone family.
Brown, Kevin M; Xu, Mai; Sargen, Michael; Jang, Hyunbum; Zhang, Mingzhen; Zhang, Tongwu; Zhu, Bin; Jones, Kristie; Kim, Jung; Mendoza, Laura; Hayward, Nicholas K; Tucker, Margaret A; Goldstein, Alisa M; Yang, Xiaohong Rose; Stewart, Douglas R; Hicks, Belynda; Consonni, Dario; Pesatori, Angela C; Fargnoli, Maria Concetta; Peris, Ketty; Stratigos, Alex; Menin, Chiara; Ghiorzo, Paola; Puig, Susana; Nagore, Eduardo; , ; Andresson, Thorkell; Nussinov, Ruth; Calista, Donato; Landi, Maria Teresa
FAMILIAL CANCER - 1/01/2021
The Prognostic Impact of Circulating Tumour DNA in Melanoma Patients Treated with Systemic Therapies-Beyond BRAF Mutant Detection.
Marsavela, Gabriela; Johansson, Peter A; Pereira, Michelle R; McEvoy, Ashleigh C; Reid, Anna L; Robinson, Cleo; Warburton, Lydia; Khattak, Muhammad A; Meniawy, Tarek M; Amanuel, Benhur; Millward, Michael; Hayward, Nicholas K; Ziman, Melanie R; Gray, Elin S; Calapre, Leslie
Cancers - 1/12/2020
Cancer Council WA - 1100249
Whole-genome sequencing of acral melanoma reveals genomic complexity and diversity.
Newell, Felicity; Wilmott, James S; Johansson, Peter A; Nones, Katia; Addala, Venkateswar; Mukhopadhyay, Pamela; Broit, Natasa; Amato, Carol M; Van Gulick, Robert; Kazakoff, Stephen H; Patch, Ann-Marie; Koufariotis, Lambros T; Lakis, Vanessa; Leonard, Conrad; Wood, Scott; Holmes, Oliver; Xu, Qinying; Lewis, Karl; Medina, Theresa; Gonzalez, Rene; Saw, Robyn P M; Spillane, Andrew J; Stretch, Jonathan R; Rawson, Robert V; Ferguson, Peter M; Dodds, Tristan J; Thompson, John F; Long, Georgina V; Levesque, Mitchell P; Robinson, William A; Pearson, John V; Mann, Graham J; Scolyer, Richard A; Waddell, Nicola; Hayward, Nicholas K
Nature Communications - 1/10/2020
National Health and Medical Research Council of Australia (NHMRC) Program Grant - 1093017
FRAMe: Familial Risk Assessment of Melanoma-a risk prediction tool to guide CDKN2A germline mutation testing in Australian familial melanoma.
Holland, Elizabeth A; Lo, Serigne; Kelly, Blake; Schmid, Helen; Cust, Anne E; Palmer, Jane M; Drummond, Martin; Hayward, Nicholas K; Pritchard, Antonia L; Mann, Graham J
FAMILIAL CANCER - 1/09/2020
National Health and Medical Research Council of Australia - Program grant 402761 and
Loss-of-function variants in POT1 predispose to uveal melanoma.
Nathan, Vaishnavi; Palmer, Jane M; Johansson, Peter A; Hamilton, Hayley R; Warrier, Sunil K; Glasson, William; McGrath, Lindsay A; Kahl, Vivian F S; Vasireddy, Raja S; Pickett, Hilda A; Brooks, Kelly M; Pritchard, Antonia L; Hayward, Nicholas K
JOURNAL OF MEDICAL GENETICS - 1/09/2020
National Health and Medical Research Council (NHMRC) - 1093017
Tumor mutation burden and structural chromosomal aberrations are not associated with T-cell density or patient survival in acral, mucosal, and cutaneous melanomas.
Edwards, Jarem; Ferguson, Peter M; Lo, Serigne N; Pires da Silva, Ines; Colebatch, Andrew J; Lee, Hansol; Saw, Robyn Pm; Thompson, John F; Menzies, Alexander M; Long, Georgina V; Newell, Felicity; Pearson, John; Waddell, Nicola; Hayward, Nicholas; Johansson, Peter A; Mann, Graham; Scolyer, Richard A; Palendira, Umaimainthan; Wilmott, James S
Cancer Immunology Research - 1/09/2020
