Safety, pharmacokinetics, and antimalarial activity of the novel triaminopyrimidine ZY-19489: a first-in-human, randomised, placebo-controlled, double-blind, single ascending dose study, pilot food-effect study, and volunteer infection study.
Barber, Bridget E; Fernandez, Melissa; Patel, Hardik Babubhai; Barcelo, Catalina; Woolley, Stephen D; Patel, Harilal; Llewellyn, Stacey; Abd-Rahman, Azrin N; Sharma, Sunil; Jain, Mukul; Ghoghari, Ashok; Di Resta, Ilaria; Fuchs, Aline; Deni, Ioanna; Yeo, Tomas; Mok, Sachel; Fidock, David A; Chalon, Stephan; Möhrle, Jörg J; Parmar, Deven; McCarthy, James S; Kansagra, Kevinkumar
The Lancet. Infectious diseases - 1/01/2022
The effect of regularly dosed acetaminophen versus no acetaminophen on renal function in Plasmodium knowlesi malaria (PACKNOW): a randomised controlled trial.
Cooper, Daniel J; Grigg, Matthew J; Plewes, Katherine; Rajahram, Giri S; Piera, Kim A; William, Timothy; Menon, Jayaram; Koleth, Glenn; Edstein, Michael D; Birrell, Geoffrey W; Wattanakul, Thanaporn; Tarning, Joel; Patel, Aatish; Yeo, Tsin Wen; Dondorp, Arjen M; Anstey, Nicholas M; Barber, Bridget E
Clinical Infectious Diseases - 1/01/2022
Transmission blocking activity of low dose tafenoquine in healthy volunteers experimentally infected with Plasmodium falciparum.
Webster, Rebecca; Mitchell, Hayley; Peters, Jenny M; Heunis, Juanita; O'Neill, Brighid; Gower, Jeremy; Lynch, Sean; Jennings, Helen; Amante, Fiona H; Llewellyn, Stacey; Marquart, Louise; Potter, Adam J; Birrell, Geoffrey W; Edstein, Michael D; Dennis Shanks, G; McCarthy, James S; Barber, Bridget E
Clinical Infectious Diseases - 1/01/2022
Quantification of Tafenoquine and 5,6-Orthoquinone Tafenoquine by UHPLC-MS/MS in Blood, Plasma, and Urine, and Application to a Pharmacokinetic Study
Birrell, Geoffrey W.; Van Breda, Karin; Barber, Bridget; Webster, Rebecca; McCarthy, James S.; Shanks, G. Dennis; Edstein, Michael D.
MOLECULES - 1/01/2022
Diagnostic accuracy and limit of detection of ten malaria parasite lactate dehydrogenase-based rapid tests for Plasmodium knowlesi and P. falciparum
Tan, Angelica F.; Sakam, Sitti Saimah Binti; Rajahram, Giri S.; William, Timothy; Isnadi, Mohammad Faruq Abd Rachman; Daim, Sylvia; Barber, Bridget E.; Kho, Steven; Sutherland, Colin J.; Anstey, Nicholas M.; Yerlikaya, Seda; van Schalkwyk, Donelly A.; Grigg, Matthew J.
Frontiers in cellular and infection microbiology - 1/01/2022
Positron emission tomography and magnetic resonance imaging of the brain in experimental human malaria, a prospective cohort study.
Woodford, John; Gillman, Ashley; Jenvey, Peter; Roberts, Jennie; Woolley, Stephen; Barber, Bridget E; Fernandez, Melissa; Rose, Stephen; Thomas, Paul; Anstey, Nicholas M; McCarthy, James S
SCIENTIFIC REPORTS - 1/01/2022
Diagnostic performance of a 5-plex malaria immunoassay in regions co-endemic for Plasmodium falciparum, P. vivax, P. knowlesi, P. malariae and P. ovale.
Kho, Steven; Anstey, Nicholas M; Barber, Bridget E; Piera, Kim; William, Timothy; Kenangalem, Enny; McCarthy, James S; Jang, Ihn Kyung; Domingo, Gonzalo J; Britton, Sumudu; Grigg, Matthew J
SCIENTIFIC REPORTS - 1/01/2022
An open dataset of Plasmodium vivax genome variation in 1,895 worldwide samples.
, ; Adam, Ishag; Alam, Mohammad Shafiul; Alemu, Sisay; Amaratunga, Chanaki; Amato, Roberto; Andrianaranjaka, Voahangy; Anstey, Nicholas M; Aseffa, Abraham; Ashley, Elizabeth; Assefa, Ashenafi; Auburn, Sarah; Barber, Bridget E; Barry, Alyssa; Batista Pereira, Dhelio; Cao, Jun; Chau, Nguyen Hoang; Chotivanich, Kesinee; Chu, Cindy; Dondorp, Arjen M; Drury, Eleanor; Echeverry, Diego F; Erko, Berhanu; Espino, Fe; Fairhurst, Rick; Faiz, Abdul; Fernanda Villegas, María; Gao, Qi; Golassa, Lemu; Goncalves, Sonia; Grigg, Matthew J; Hamedi, Yaghoob; Hien, Tran Tinh; Htut, Ye; Johnson, Kimberly J; Karunaweera, Nadira; Khan, Wasif; Krudsood, Srivicha; Kwiatkowski, Dominic P; Lacerda, Marcus; Ley, Benedikt; Lim, Pharath; Liu, Yaobao; Llanos-Cuentas, Alejandro; Lon, Chanthap; Lopera-Mesa, Tatiana; Marfurt, Jutta; Michon, Pascal; Miotto, Olivo; Mohammed, Rezika; Mueller, Ivo; Namaik-Larp, Chayadol; Newton, Paul N; Nguyen, Thuy-Nhien; Nosten, Francois; Noviyanti, Rintis; Pava, Zuleima; Pearson, Richard D; Petros, Beyene; Phyo, Aung P; Price, Ric N; Pukrittayakamee, Sasithon; Rahim, Awab Ghulam; Randrianarivelojosia, Milijaona; Rayner, Julian C; Rumaseb, Angela; Siegel, Sasha V; Simpson, Victoria J; Thriemer, Kamala; Tobon-Castano, Alberto; Trimarsanto, Hidayat; Urbano Ferreira, Marcelo; Vélez, Ivan D; Wangchuk, Sonam; Wellems, Thomas E; White, Nicholas J; William, Timothy; Yasnot, Maria F; Yilma, Daniel
Wellcome open research - 1/01/2022
Geographical distribution and genetic diversity of Plasmodium vivax reticulocyte binding protein 1a correlates with patient antigenicity.
Park, Ji-Hoon; Kim, Min-Hee; Sutanto, Edwin; Na, Seok-Won; Kim, Min-Jae; Yeom, Joon Sup; Nyunt, Myat Htut; Abbas Elfaki, Mohammed Mohieldien; Abdel Hamid, Muzamil Mahdi; Cha, Seok Ho; Alemu, Sisay Getachew; Sriprawat, Kanlaya; Anstey, Nicholas M; Grigg, Matthew J; Barber, Bridget E; William, Timothy; Gao, Qi; Liu, Yaobao; Pearson, Richard D; Price, Ric N; Nosten, Francois; Yoon, Sung-Il; No, Joo Hwan; Han, Eun-Taek; Auburn, Sarah; Russell, Bruce; Han, Jin-Hee
PLOS NEGLECTED TROPICAL DISEASES - 1/01/2022
Plasmodium vivax malaria serological exposure markers: Assessing the degree and implications of cross-reactivity with P. knowlesi.
Longley, Rhea J; Grigg, Matthew J; Schoffer, Kael; Obadia, Thomas; Hyslop, Stephanie; Piera, Kim A; Nekkab, Narimane; Mazhari, Ramin; Takashima, Eizo; Tsuboi, Takafumi; Harbers, Matthias; Tetteh, Kevin; Drakeley, Chris; Chitnis, Chetan E; Healer, Julie; Tham, Wai-Hong; Sattabongkot, Jetsumon; White, Michael T; Cooper, Daniel J; Rajahram, Giri S; Barber, Bridget E; William, Timothy; Anstey, Nicholas M; Mueller, Ivo
Cell reports. Medicine - 1/01/2022
Plasmodium knowlesi detection methods for human infections-Diagnosis and surveillance.
Grigg, Matthew J; Lubis, Inke N; Tetteh, Kevin K A; Barber, Bridget E; William, Timothy; Rajahram, Giri S; Tan, Angelica F; Sutherland, Colin J; Noviyanti, Rintis; Drakeley, Chris J; Britton, Sumudu; Anstey, Nicholas M
ADVANCES IN PARASITOLOGY - 1/01/2021
An Evaluation of Commonly Used Surrogate Baseline Creatinine Values to Classify AKI During Acute Infection.
Cooper, Daniel J; Plewes, Katherine; Grigg, Matthew J; Patel, Aatish; Rajahram, Giri S; William, Timothy; Hiemstra, Thomas F; Wang, Zhiqiang; Barber, Bridget E; Anstey, Nicholas M
KIDNEY INTERNATIONAL REPORTS - 1/01/2021
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Co-administered Ruxolitinib and Artemether-Lumefantrine in Healthy Adults.
Chughlay, M Farouk; Barnes, Karen I; El Gaaloul, Myriam; Abla, Nada; Möhrle, Jörg J; Griffin, Paul; van Giersbergen, Paul; Reuter, Stephanie E; Schultz, Hayley B; Kress, Anita; Tapley, Peter; Webster, Rebecca A; Wells, Timothy; McCarthy, James S; Barber, Bridget E; Marquart, Louise; Boyle, Michelle J; Engwerda, Christian R; Chalon, Stephan
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY - 1/01/2021
Safety, infectivity and immunogenicity of a genetically attenuated blood-stage malaria vaccine.
Webster, Rebecca; Sekuloski, Silvana; Odedra, Anand; Woolley, Stephen; Jennings, Helen; Amante, Fiona; Trenholme, Katharine R; Healer, Julie; Cowman, Alan F; Eriksson, Emily M; Sathe, Priyanka; Penington, Jocelyn; Blanch, Adam J; Dixon, Matthew W A; Tilley, Leann; Duffy, Michael F; Craig, Alister; Storm, Janet; Chan, Jo-Anne; Evans, Krystal; Papenfuss, Anthony T; Schofield, Louis; Griffin, Paul; Barber, Bridget E; Andrew, Dean; Boyle, Michelle J; de Labastida Rivera, Fabian; Engwerda, Christian; McCarthy, James S
BMC MEDICINE - 1/01/2021
Reduced circulating dendritic cells in acute Plasmodium knowlesi and Plasmodium falciparum malaria despite elevated plasma Flt3 ligand levels.
Loughland, Jessica R; Woodberry, Tonia; Oyong, Damian; Piera, Kim A; Amante, Fiona H; Barber, Bridget E; Grigg, Matthew J; William, Timothy; Engwerda, Christian R; Anstey, Nicholas M; McCarthy, James S; Boyle, Michelle J; Minigo, Gabriela
MALARIA JOURNAL - 1/01/2021
