Abstract

This assessment by the Environmental Effects Assessment Panel (EEAP) of the Montreal Protocol under the United Nations Environment Programme (UNEP) evaluates the effects of ultraviolet (UV) radiation on human health within the context of the Montreal Protocol and its Amendments. We assess work published since our last comprehensive assessment in 2018. Over the last four years gains have been made in knowledge of the links between sun exposure and health outcomes, mechanisms, and estimates of disease burden, including economic impacts. Of particular note, there is new information about the way in which exposure to UV radiation modulates the immune system, causing both harms and benefits for health. The burden of skin cancer remains high, with many lives lost to melanoma and many more people treated for keratinocyte cancer, but it has been estimated that the Montreal Protocol will prevent 11 million cases of melanoma and 432 million cases of keratinocyte cancer that would otherwise have ...

Authors	Neale, RE; Lucas, RM; Byrne, SN; Hollestein, L; Rhodes, LE; Yazar, S; Young, AR; Berwick, M; Ireland, RA; Olsen, CM
Journal	Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology
Pages	1011-1047
Volume	22
Date	1/04/2023
Grant ID
Funding Body
URL	http://www.ncbi.nlm.nih.gov/pubmed/?term=10.1007/s43630-023-00375-8