QIMR Berghofer

The effect of polygenic liability to mental disorders on COVID-19 outcomes in people with depression: the mediating role of anxiety.

Abstract

Genetic vulnerability to mental disorders has been associated with coronavirus disease-19 (COVID-19) outcomes. We explored whether polygenic risk scores (PRSs) for several mental disorders predicted poorer clinical and psychological COVID-19 outcomes in people with pre-existing depression.

Authors Monistrol-Mula, A; Felez-Nobrega, M; Byrne, EM; Lind, PA; Hickie, IB; Martin, NG; Medland, SE; Colodro-Conde, L; Mitchell, BL
Journal PSYCHOLOGICAL MEDICINE
Pages 1-10
Volume
Date 18/12/2024
Grant ID
Funding Body
URL http://www.ncbi.nlm.nih.gov/pubmed/?term=10.1017/S0033291724001983