QIMR Berghofer

Patterns of associations with epidemiologic factors by high grade serous ovarian cancer gene expression subtypes.

Abstract

Ovarian high-grade serous carcinomas (HGSC) comprise four distinct molecular subtypes based on mRNA expression patterns, with differential survival. Understanding risk factor associations is important to elucidate the etiology of HGSC. We investigated associations between different epidemiologic risk factors and HGSC molecular subtypes.

Authors Collin, LJ; Cushing-Haugen, KL; Terry, KL; Goode, EL; Wu, AH; Harris, HR; Sasamoto, N; Cramer, DW; Modugno, F; Elishaev, E; Fu, Z; Moysich, KB; Fasching, PA; Pearce, CL; Menon, U; Gentry-Maharaj, A; Gayther, SA; Wentzensen, N; Goodman, MT; George, J; Talhouk, A; Anglesio, MS; Ramus, SJ; Bowtell, DD; Tworoger, SS; Schildkraut, JM; Webb, PM; Doherty, JA
Journal Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Pages
Volume
Date 26/03/2025
Grant ID P30 CA015083 | NCI NIH HHS [CA] (United States); P50 CA136393 | NCI NIH HHS [CA] (United States); R01 CA248288 | NCI NIH HHS [CA] (United States)
Funding Body
URL http://www.ncbi.nlm.nih.gov/pubmed/?term=10.1158/1055-9965.EPI-24-1143