Opisthorchis viverrini (OV) and soil-transmitted helminths (STH) are two of the most common helminths contributing to the Neglected Tropical Disease (NTDs) burden in the Lower Mekong Basin. Although mass drug administration is the cornerstone of control programs to reduce morbidity caused by these infections, this approach has limitations in preventing re-infections. Elimination requires additional measures such as reservoir host treatment, improved hygiene and health education to reinforce MDA's impact. This study aims to examine the impact of a scalable multi-component One Health Helminth Elimination program in the Lower Mekong Basin (HELM) that combines human praziquantel (PZQ) and albendazole (ALB) treatment with a program that includes the "Magic Glasses" and the "Lawa Model" interventions with health promotion at their core.
| Authors | Mationg, ML; Clements, ACA; Williams, GM; Kelly, M; Stewart, DE; Gordon, CA; Wangdi, K; Tangkawattana, S; Suwannatrai, AT; Savathdy, V; Khieu, V; Wannachart, S; O'Connor, SY; Forsyth, S; Gannon, S; Odermatt, P; McManus, DP; Sayasone, S; Khieu, V; Sripa, B; Gray, DJ |
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| Journal | Trials |
| Pages | 801 |
| Volume | 25 |
| Date | 28/12/2024 |
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| URL | http://www.ncbi.nlm.nih.gov/pubmed/?term=10.1186/s13063-024-08616-6 |