Abstract

Regulatory T cells (Tregs) are the main mediators of peripheral tolerance. Treg-directed therapy has shown promising results in preclinical studies of diverse immunopathologies. At present, the clinical applicability of adoptive Treg transfer is limited by difficulties in generating Tregs at sufficient cell dose and purity.

Authors	Ekwe, AP; Au, RY; Zhang, P; Mcenroe, BA; Tan, ML; Saldan, A; Henden, AS; Hutchins, CJ; Henderson, A; Mudie, K; Kerr, K; Fuery, M; Kennedy, GA; Hill, GR; Tey, SK
Journal	Cytotherapy
Pages	719-728
Volume	26
Date	5/04/2024
Grant ID
Funding Body
URL	http://www.ncbi.nlm.nih.gov/pubmed/?term=10.1016/j.jcyt.2024.02.023