An adult wild-type C57BL/6J mouse model of chikungunya virus (CHIKV) infection and disease has been extensively used to study the alphaviral arthritic immunopathology and to evaluate new interventions. How well mouse models recapitulate the gene expression profiles seen in humans remains controversial.
Authors | Bishop, CR; Caten, FT; Nakaya, HI; Suhrbier, A |
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Journal | Frontiers in Immunology |
Pages | |
Volume | 13 |
Date | 12/01/2022 |
Grant ID | |
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URL | http://www.ncbi.nlm.nih.gov/pubmed/?term=10.3389/fimmu.2022.1092370 |