QIMR Berghofer

The association between trauma exposure, polygenic risk and individual depression symptoms.

Abstract

Traumatic experiences are associated with increased risk for major depressive disorder (MDD). This study sought to determine the extent that trauma exposure, depression polygenic risk scores (PRS), and their interaction are associated with MDD and individual depression symptoms.

Authors Thorp, JG; Gerring, ZF; Colodro-Conde, L; Byrne, EM; Medland, SE; Middeldorp, CM; Derks, EM
Journal Psychiatry research
Pages 115101
Volume 321
Date 9/03/2023
Grant ID R56 AG068026 | NIA NIH HHS [AG] (United States)
Funding Body
URL http://www.ncbi.nlm.nih.gov/pubmed/?term=10.1016/j.psychres.2023.115101