Abstract

Accurate diagnosis of bipolar disorder (BPD) is difficult in clinical practice, with an average delay between symptom onset and diagnosis of about 7 years. A depressive episode often precedes the first manic episode, making it difficult to distinguish BPD from unipolar major depressive disorder (MDD).

Authors	Panagiotaropoulou, G; Hellberg, KG; Coleman, JRI; Seok, D; Kalman, J; Bipolar Disorder Working Group of the Psychiatric Genomics Consortium; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; iPSYCH Study Consortium; Mitchell, PB; Schofield, PR; Forstner, AJ; Bauer, M; Scott, LJ; Pato, CN; Pato, MT; Li, QS; Kirov, G; Landén, M; Jonsson, L; Müller-Myhsok, B; Smoller, JW; Binder, EB; Brückl, TM; Czamara, D; Van der Auwera, S; Grabe, HJ; Homuth, G; Schmidt, CO; Potash, JB; DePaulo, JR; Goes, FS; MacKinnon, DF; Mondimore, FM; Weissman, MM; Shi, J; Frye, MA; Biernacka, JM; Reif, A; Witt, SH; Kahn, RR; Boks, MM; Owen, MJ; Gordon-Smith, K; Mitchell, BL; Martin, NG; Medland, SE; Jones, L; Knowles, JA; Levinson, DF; O'Donovan, MC; Lewis, CM; Breen, G; Werge, T; Schork, AJ; Ophoff, RA; Ripke, S; Olde Loohuis, L
Journal	The British Journal Of Psychiatry : The Journal Of Mental Science
Pages	1-12
Volume
Date	14/02/2025
Grant ID	1/3 Psychiatric GWAS Consortium: Advancing Discove | NIMH NIH HHS [MH] (United States); 1R01MH124873-01 (to SR) | NIMH NIH HHS [MH] (United States); R00MH116115 (to LMOL) | NIMH NIH HHS [MH] (United States)
Funding Body
URL	http://www.ncbi.nlm.nih.gov/pubmed/?term=10.1192/bjp.2024.125