Endometrial cancer is one of the few cancers for which mortality is still increasing. A lack of treatment options remains a major challenge, particularly for some subtypes of the disease. GZD824, also known as olverembatinib, is a multi-kinase inhibitor previously investigated in clinical trials for chronic myeloid leukaemia and Ph+ acute lymphoblastic leukaemia as a BCR-ABL inhibitor. This study aimed to investigate the pre-clinical efficacy of GZD824 for the treatment of EC.
Authors | Liu, D; Glubb, D; O'Mara, T; Ford, CE |
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Journal | Cancer medicine |
Pages | e70531 |
Volume | 14 |
Date | 1/01/2025 |
Grant ID | APP1173170 | National Health and Medical Research Council; UNSW Med & Health ECAN seed grant |
Funding Body | |
URL | http://www.ncbi.nlm.nih.gov/pubmed/?term=10.1002/cam4.70531 |