Pancreatic ductal adenocarcinoma (PDAC) has a high incidence of perineural invasion (PNI), a pathological feature of the cancer invasion of nerves. PNI is associated with a poor prognosis, local recurrence and cancer pain. It has been suggested that interactions between nerves and the tumor microenvironment (TME) play a role in PDAC tumorigenesis.
| Authors | Lakis, V; Chan, NL; Lyons, R; Blackburn, N; Nguyen, TH; Chang, C; Masel, A; West, NP; Boyle, GM; Patch, AM; Gill, AJ; Nones, K |
|---|---|
| Journal | Cancers |
| Pages | |
| Volume | 17 |
| Date | 1/04/2025 |
| Grant ID | 20.R6.COL.KN.QIMR.28.4 | PanKind Pancreatic Cancer Foundation and Tour de Cure |
| Funding Body | |
| URL | http://www.ncbi.nlm.nih.gov/pubmed/?term=10.3390/cancers17050852 |