Ferroptosis is a form of regulated cell death characterised by lipid peroxidation as the terminal endpoint and a requirement for iron. Although it protects against cancer and infection, ferroptosis is also implicated in causing neuronal death in degenerative diseases of the central nervous system (CNS). The precise role for ferroptosis in causing neuronal death is yet to be fully resolved.
Authors | Liddell, JR; Hilton, JBW; Kysenius, K; Billings, JL; Nikseresht, S; McInnes, LE; Hare, DJ; Paul, B; Mercer, SW; Belaidi, AA; Ayton, S; Roberts, BR; Beckman, JS; McLean, CA; White, AR; Donnelly, PS; Bush, AI; Crouch, PJ |
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Journal | MOLECULAR NEURODEGENERATION |
Pages | 14 |
Volume | 19 |
Date | 5/03/2024 |
Grant ID | |
Funding Body | |
URL | http://www.ncbi.nlm.nih.gov/pubmed/?term=10.1186/s13024-023-00691-8 |