Abstract

BACKGROUND: This study: (i) assessed compliance with a consensus set of quality indicators (QIs) in pancreatic cancer (PC); and (ii) evaluated the association between compliance with these QIs and survival. METHODS: Four years of data were collected for patients diagnosed with PC. Cox proportional hazards models were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs). A multivariable analysis tested the relationship between significant patient and hospital characteristics, patient cluster effects within hospitals and survival. RESULTS: 1061 patients were eligible for this study. Significant association with improved survival were: (i) in the potentially resectable group having adjuvant chemotherapy administered following surgery or a reason documented (HR, 0.29; 95 CI, 0.19-0.46); (ii) in the locally advanced group included having chemotherapy ± chemoradiation, or a reason documented for not undergoing treatment (HR, 0.38; 95 CI, 0.25-0.58); and (iii) in the metastatic disease group included having documented performance status at presentation (HR, 0.65; 95 CI, 0.47-0.89), being seen by an oncologist in the absence of treatment (HR, 0.48; 95 CI, 0.31-0.77), and disease management discussed at a multidisciplinary team meeting (HR, 0.79; 95 CI, 0.64-0.96). CONCLUSION: Capture of a concise data set has enabled quality of care to be assessed.

Authors	Maharaj, Ashika D; Evans, Sue M; Ioannou, Liane J; Croagh, Daniel; Earnest, Arul; Holland, Jennifer F; Pilgrim, Charles H C; Neale, Rachel E; Goldstein, David; Kench, James G; Merrett, Neil D; White, Kate; Burmeister, Elizabeth A; Evans, Peter M; Hayes, Theresa M; Houli, Nezor; Knowles, Brett; Leong, Trevor; Nikfarjam, Mehrdad; Philip, Jennifer; Quinn, Maddy; Shapiro, Jeremy; Smith, Marty D; Spillane, John B; Wong, Rachel; Zalcberg, John R
Journal	Hpb : The Official Journal Of The International Hepato Pancreato Biliary Association
Pages	950-962
Volume	24
Date	1/01/2021
Grant ID
Funding Body
URL	http://www.ncbi.nlm.nih.gov/pubmed/?term=10.1016/j.hpb.2021.11.005