T and NK cells were crucial to the vaccine-elicited tumor regression. Individualized autologous tumor antigen vaccines based on effective activation of the innate immune system by bacterial cytoplasmic membranes hold great potential for personalized treatment of postoperative patients with cancer.
Authors | Chen, Long; Qin, Hao; Zhao, Ruifang; Zhao, Xiao; Lin, Liangru; Chen, Yang; Lin, Yixuan; Li, Yao; Qin, Yuting; Li, Yiye; Liu, Shaoli; Cheng, Keman; Chen, Hanqing; Shi, Jian; Anderson, Gregory J; Wu, Yan; Zhao, Yuliang; Nie, Guangjun |
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Journal | Science Translational Medicine |
Pages | |
Volume | 13 |
Date | 1/01/2021 |
Grant ID | |
Funding Body | |
URL | http://www.ncbi.nlm.nih.gov/pubmed/?term=10.1126/scitranslmed.abc2816 |