Abstract

(PSA) lectins captured the highest number of validated candidate glycoproteins. Secondly, we independently validated serum LeMBA-MS/MS results by demonstrating the in situ relationship of lectin-binding with tumor cells. Using lectin-histochemistry and immunohistochemistry (IHC) for key proteins on tissues with HSA and semi-quantitation of the signals, we demonstrate that a combination of DSA histochemistry and IHC for complement C7 greatly increases the prospect of a more specific diagnosis of canine HSA.

Authors	Oungsakul, Patharee; Choi, Eunju; Shah, Alok K; Mohamed, Ahmed; O'Leary, Caroline; Duffy, David; Hill, Michelle M; Bielefeldt-Ohmann, Helle
Journal	Veterinary sciences
Pages
Volume	8
Date	1/01/2021
Grant ID
Funding Body
URL	http://www.ncbi.nlm.nih.gov/pubmed/?term=10.3390/vetsci8030038