Comparing empirical kinship derived heritability for imaging genetics traits in the UK biobank and human connectome project.
Abstract
). In summary, the hardware-accelerated FPHI made it practical to calculate heritability values for voxel-wise neuroimaging traits, even in very large samples such as the UKBB. The patterns of additive genetic variance in neuroimaging traits measured in a large sample of related and unrelated individuals showed excellent agreement regardless of the estimation method. The code and instruction to execute these analyses are available at www.solar-eclipse-genetics.org.
| Authors | Gao, Si; Donohue, Brian; Hatch, Kathryn S; Chen, Shuo; Ma, Tianzhou; Ma, Yizhou; Kvarta, Mark D; Bruce, Heather; Adhikari, Bhim M; Jahanshad, Neda; Thompson, Paul M; Blangero, John; Hong, L Elliot; Medland, Sarah E; Ganjgahi, Habib; Nichols, Thomas E; Kochunov, Peter |
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| Journal | NEUROIMAGE |
| Pages | 118700 |
| Volume | 245 |
| Date | 1/01/2021 |
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| URL | http://www.ncbi.nlm.nih.gov/pubmed/?term=10.1016/j.neuroimage.2021.118700 |