Widespread discrepancy in Nnt genotypes and genetic backgrounds complicates granzyme A and other knockout mouse studies.

Abstract

and C57BL/6N background issues have clearly complicated our understanding of GZMA and may similarly have influenced studies across a broad range of fields.

Authors Rawle, Daniel J; Le, Thuy T; Dumenil, Troy; Bishop, Cameron; Yan, Kexin; Nakayama, Eri; Bird, Phillip I; Suhrbier, Andreas
Journal Elife
Pages
Volume 11
Date 1/01/2022
Grant ID
Funding Body
URL http://www.ncbi.nlm.nih.gov/pubmed/?term=10.7554/eLife.70207