Abstract

The RTS,S vaccine has recently been recommended for implementation as a childhood vaccine in regions with moderate-to-high malaria transmission. We discuss mechanisms of vaccine protection and longevity, implemen-tation considerations, and future research needed to increase the vaccine's health impact, including vaccine modifications for higher efficacy and longevity of protection.

Authors	Beeson, James G.; Kurtovic, Liriye; Valim, Clarissa; Asante, Kwaku Poku; Boyle, Michelle J.; Mathanga, Don; Dobano, Carlota; Moncunill, Gemma
Journal	Science Translational Medicine
Pages
Volume	14
Date	1/01/2022
Grant ID
Funding Body
URL	http://www.ncbi.nlm.nih.gov/pubmed/?term=10.5485/sci.8748