The interactions between cancer cells and immune cells are complex and context dependent. Choosing the right model to study these interactions is a crucial step in the development of immunotherapies. From cell co-cultures to organoids, organs-on-chip, and a variety of mouse models, experts share their model of choice for immuno-oncology research and discuss their strengths and caveats.
Authors | Kuo, Calvin J.; Voest, Emile; Parrini, Maria Carla; Zou, Weiping; Teng, Michele W. L.; Greten, Tim F.; Palucka, Karolina; Gill, Saar; Joshi, Nikhil S. |
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Journal | CANCER CELL |
Pages | 145-147 |
Volume | 38 |
Date | 1/08/2020 |
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URL | http://www.ncbi.nlm.nih.gov/pubmed/?term=10.1016/j.ccell.2020.07.010 |
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