Eomes-Dependent Loss of the Co-activating Receptor CD226 Restrains CD8+ T Cell Anti-tumor Functions and Limits the Efficacy of Cancer Immunotherapy.
Abstract
T cell function and limits the efficacy of cancer immunotherapy.
| Authors | Weulersse, Marianne; Asrir, Assia; Pichler, Andrea C; Lemaitre, Lea; Braun, Matthias; Carrié, Nadège; Joubert, Marie-Véronique; Le Moine, Marie; Do Souto, Laura; Gaud, Guillaume; Das, Indrajit; Brauns, Elisa; Scarlata, Clara M; Morandi, Elena; Sundarrajan, Ashmitha; Cuisinier, Marine; Buisson, Laure; Maheo, Sabrina; Kassem, Sahar; Agesta, Arantxa; Pérès, Michaël; Verhoeyen, Els; Martinez, Alejandra; Mazieres, Julien; Dupré, Loïc; Gossye, Thomas; Pancaldi, Vera; Guillerey, Camille; Ayyoub, Maha; Dejean, Anne S; Saoudi, Abdelhadi; Goriely, Stanislas; Avet-Loiseau, Hervé; Bald, Tobias; Smyth, Mark J; Martinet, Ludovic |
|---|---|
| Journal | IMMUNITY |
| Pages | 824-839.e10 |
| Volume | 53 |
| Date | 1/10/2020 |
| Grant ID | PGA1-20160203788 |
| Funding Body | Fondation ARC |
| URL | http://www.ncbi.nlm.nih.gov/pubmed/?term=10.1016/j.immuni.2020.09.006 |