Continuous pre- and post-transplant exposure to a disease-associated gut microbiome promotes hyper-acute graft-versus-host disease in wild-type mice.
Abstract
: These results clarify the importance of the peri-transplant microbiome in the susceptibility to acute GVHD post-transplant and demonstrate the species-specific nature of this association.
| Authors | Bowerman, Kate L; Varelias, Antiopi; Lachner, Nancy; Kuns, Rachel D; Hill, Geoffrey R; Hugenholtz, Philip |
|---|---|
| Journal | Gut Microbes |
| Pages | 1-17 |
| Volume | 11 |
| Date | 1/01/2020 |
| Grant ID | 1129969 |
| Funding Body | Cancer Council Queensland project grant |
| URL | http://www.ncbi.nlm.nih.gov/pubmed/?term=10.1080/19490976.2019.1705729 |
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