QIMR Berghofer

Prolonged stable disease in a uveal melanoma patient with germline MBD4 nonsense mutation treated with pembrolizumab and ipilimumab.

Abstract

), implying a potential role as UM predisposition gene. These findings provide a strong basis for the inclusion of MBD4 in the screening of potential UM-prone families as well as stratification of immunotherapy.

Authors Johansson, Peter A; Stark, Andrew; Palmer, Jane M; Bigby, Kieron; Brooks, Kelly; Rolfe, Olivia; Pritchard, Antonia L; Whitehead, Kevin; Warrier, Sunil; Glasson, William; Hayward, Nicholas K
Journal IMMUNOGENETICS
Pages 433-436
Volume 71
Date 1/02/2019
Grant ID 1093017
Funding Body National Health and Medical Research Council
URL http://www.ncbi.nlm.nih.gov/pubmed/?term=10.1007/s00251-019-01108-x