QIMR Berghofer

Progression of Disease Within 24 Months in Follicular Lymphoma Is Associated With Reduced Intratumoral Immune Infiltration

Abstract

PURPOSE Understanding the immunobiology of the 15% to 30% of patients with follicular lymphoma (FL) who experience progression of disease within 24 months (POD24) remains a priority. Solid tumors with low levels of intratumoral immune infiltration have inferior outcomes. It is unknown whether a similar relationship exists between POD24 in FL.

Authors Tobin, Joshua W. D.; Keane, Colm; Gunawardana, Jay; Mollee, Peter; Birch, Simone; Thanh Hoang; Lee, Justina; Li, Li; Huang, Li; Murigneux, Valentine; Fink, J. Lynn; Matigian, Nicholas; Vari, Frank; Francis, Santiyagu; Kridel, Robert; Weigert, Oliver; Haebe, Sarah; Jurinovic, Vindi; Klapper, Wolfram; Steidl, Christian; Sehn, Laurie H.; Law, Soi-Cheng; Wykes, Michelle N.; Gandhi, Maher K.
Journal JOURNAL OF CLINICAL ONCOLOGY
Pages 3300-3309
Volume 37
Date 1/12/2019
Grant ID
Funding Body Australian National Health and Medical Research Council
URL http://www.ncbi.nlm.nih.gov/pubmed/?term=10.1200/JCO.18.02365
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