QIMR Berghofer

Overlapping genetic architecture between Parkinson disease and melanoma.

Abstract

) and highlight seven genes including PIEZO1, TRAPPC2L, and SOX6 as potential mediators of the genetic correlation between melanoma and PD. These findings demonstrate specific, shared genetic architecture between PD and melanoma that manifests at the level of gene expression.

Authors Dube, Umber; Ibanez, Laura; Budde, John P; Benitez, Bruno A; Davis, Albert A; Harari, Oscar; Iles, Mark M; Law, Matthew H; Brown, Kevin M; , ; , ; Cruchaga, Carlos
Journal Acta Neuropathologica
Pages 347-364
Volume 139
Date 1/12/2019
Grant ID P01AG003991
Funding Body National Institutes of Health (US)
URL http://www.ncbi.nlm.nih.gov/pubmed/?term=10.1007/s00401-019-02110-z