Acquired melanocytic naevus phenotypes and MC1R genotypes in Han Chinese: a cross-sectional study

Abstract

Background Early detection and treatment are the most important elements in reducing the incidence of melanoma deaths. Acquired melanocytic naevi (AMN) are well-known precursors of melanoma but most of our knowledge on the clinico- dermoscopic phenotypes of AMN is based on studies in European-background populations, particularly American and Australian populations. There has been little research in Chinese Han populations on clinico-dermoscopic variability of naevi or how naevi are affected by melanoma-linked variants of the melanocortin 1 receptor (MC1R ) gene.

Authors Li, Xiaohong; Lee, Katie J.; Duffy, David L.; Xu, Dandan; Basude, Madhur Eshwar Rao; Hu, Ying; Zhang, Hang; Jagirdar, Kasturee; Soyer, H. Peter; Dong, Huiting; Sturm, Richard A.
Journal PEERJ
Pages e4168
Volume 5
Date 1/12/2017
Grant ID
Funding Body Fund for the Science and Technology Program of the Personnel Having Studied Abroad by the Chinese Ministry of Human Resource and Social Security
URL http://www.ncbi.nlm.nih.gov/pubmed/?term=10.7717/peerj.4168