Cerebellar atrophy in neurodegeneration-a meta-analysis

Abstract

Introduction The cerebellum has strong cortical and subcortical connectivity, but is rarely taken into account for clinical diagnosis in many neurodegenerative conditions, particularly in the absence of clinical ataxia. The current meta-analysis aims to assess patterns of cerebellar grey matter atrophy in seven neurodegenerative conditions (Alzheimer's disease (AD), Parkinson's disease (PD) and Huntington's disease (HD), frontotemporal dementia (FTD), amyotrophic lateral sclerosis (ALS), multiple system atrophy (MSA), progressive supranuclear palsy (MSP)).

Authors Gellersen, Helena M.; Guo, Christine C.; O'Callaghan, Claire; Tan, Rachel H.; Sami, Saber; Hornberger, Michael
Journal JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
Pages 780-788
Volume 88
Date 1/09/2017
Grant ID GNT1091310
Funding Body National Health and Medical Research Council Neil Hamilton Fairley Fellowship
URL http://www.ncbi.nlm.nih.gov/pubmed/?term=10.1136/jnnp-2017-315607