QIMR Berghofer

Pocket-sized iron regulators: one size fits all?

Abstract

In this issue of Blood, Casu et al report on results from their studies on potential therapeutic options to restrict iron as a treatment of 2 differing blood disorders: the anemia and iron overload associated with b-thalassemia, and the erythrocytosis associated with polycythemia vera (PV). They examine the use of derivatives of hepcidin, a 25-amino acid peptide secreted by the liver, which is widely accepted as the "iron stores" regulator.(1)

Authors Subramaniam, V. Nathan
Journal BLOOD
Pages 153-154
Volume 128
Date 1/07/2016
Grant ID
Funding Body
URL http://www.ncbi.nlm.nih.gov/pubmed/?term=10.1182/blood-2016-05-716043
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