QIMR Berghofer

EBC-318 and 339: bicyclo[10.2.1]alkanes from Croton insularis

Abstract

Two new crotinsulidanes EBC-318 and EBC-339 were isolated from the Australian rain forest plant Croton insularis. Both compounds are characterised by a bicyclo[10.2.1]alkane skeleton, one of which contains a bridgehead double bond. Cancer cell line cytotoxicity and biosynthetic considerations are presented.

Authors Maslovskaya, Lidia A.; Savchenko, Andrei I.; Gordon, Victoria A.; Reddell, Paul W.; Pierce, Carly J.; Parsons, Peter G.; Williams, Craig M.
Journal RSC ADVANCES
Pages 25110-25113
Volume 6
Date 1/01/2016
Grant ID
Funding Body EcoBiotics Ltd.
URL http://www.ncbi.nlm.nih.gov/pubmed/?term=10.1039/c6ra02599d